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Case Reports
. 2018 Apr 4;10(4):e2425.
doi: 10.7759/cureus.2425.

Mesalamine Associated Bradycardia

Michael Krzyzak  1 , Anupam Gupta  1 , Evgeny Antonov  2 , Stephen M Mulrooney  3
Affiliations
Case Reports

Mesalamine Associated Bradycardia

Michael Krzyzak et al. Cureus. .

Abstract

A 38-year-old female presented with an acute flare of ulcerative colitis. She was started on prednisone and mesalamine. Within 24 hours of initiating mesalamine, she developed sinus bradycardia. After holding mesalamine, the heart rate returned to normal within five days. Our case illustrates the third described case, to our knowledge, of severe sinus bradycardia secondary to mesalamine.

Keywords: bradycardia; drug side effects; ulcerative colitis.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Computed Tomography of the Abdomen
Circumferential wall thickening and mucosal hyperenhancement of the sigmoid colon and the rectum with surrounding inflammatory changes and several subcentimeter pericolonic lymph nodes (blue arrow).
Figure 2
Figure 2. Electrocardiogram Showing Sinus Bradycardia
See this image and copyright information in PMC

References

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