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. 1985 Jun;62(6):816-22.
doi: 10.3171/jns.1985.62.6.0816.

Prediction of survival in glioma patients by means of positron emission tomography

N J Patronas, G Di Chiro, C Kufta, D Bairamian, P L Kornblith, R Simon, S M Larson

Prediction of survival in glioma patients by means of positron emission tomography

N J Patronas et al. J Neurosurg. 1985 Jun.

Abstract

The aim of this study was to determine whether positron emission tomography (PET) with fluorine-18 (18F)-2-deoxyglucose (FDG) can be used as a prognostic test in patients with high-grade cerebral gliomas, regardless of the treatment given. Forty-five patients with astrocytoma Grade III or IV were included in this analysis. The mean survival time of patients with tumors exhibiting high glucose utilization as determined by PET-FDG was 5 months, whereas patients with gliomas showing lower glucose utilization had a mean survival period of 19 months. It is postulated that PET-FDG scans reflect the biological behavior of high-grade astrocytomas and may be used to predict the survival time of patients harboring such neoplasms.

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