Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 May-Jun;40(3):239-246.
doi: 10.4103/IJPSYM.IJPSYM_561_17.

Anxiety, Depression, and Quality of Life in Women with Polycystic Ovarian Syndrome

Affiliations

Anxiety, Depression, and Quality of Life in Women with Polycystic Ovarian Syndrome

Aditi P Chaudhari et al. Indian J Psychol Med. 2018 May-Jun.

Abstract

Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder among women of reproductive age. Symptoms include amenorrhea, hirsutism, infertility, obesity, acne vulgaris, and androgenic alopecia. PCOS is a stigmatizing condition that affects a woman's identity, mental health and quality of life (QOL). This aspect has not received adequate attention in India.

Aims and objectives: (1) To study the prevalence of anxiety and depression among women suffering from PCOS (2) To determine if symptoms of PCOS were associated with psychiatric morbidity, and (3) To determine the impact of psychiatric morbidity on the QOL.

Materials and methods: Seventy females in the reproductive age group (18-45 years) diagnosed with PCOS as per Rotterdam criteria and without any preexisting psychiatric illness were clinically interviewed for anxiety and depressive disorders which were then rated according to the Hamilton scales. QOL was assessed using the World Health Organization-QOL-BREF. Binary logistic regression was performed to study the association of the symptoms with the psychiatric morbidity. QOL scores of patients with and without psychiatric morbidity were compared using Mann-Whitney U-test.

Results and conclusions: The prevalence of anxiety and depression in our sample was 38.6% and 25.7%, respectively. Infertility and alopecia were associated with anxiety, while acne was associated with depression. Hirsutism was associated with a lower psychological QOL. Patients with psychiatric morbidity had a significantly lower QOL than those without.

Keywords: Anxiety; depression; polycystic ovarian syndrome; quality of life; symptomatology.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
The prevalence of the symptoms of polycystic ovarian syndrome in the study sample
Figure 2
Figure 2
Number of symptoms experienced by the patients (n = 70)

References

    1. Malik-Aslam A, Reaney MD, Speight J. The suitability of polycystic ovary syndrome-specific questionnaires for measuring the impact of PCOS on quality of life in clinical trials. Value Health. 2010;13:440–6. - PubMed
    1. Malik S, Jain K, Talwar P, Prasad S, Dhorepatil B, Gouri Devi. Management of polycystic ovary syndrome in India. Fertil Sci Res. 2014;1:23–43.
    1. Månsson M, Holte J, Landin-Wilhelmsen K, Dahlgren E, Johansson A, Landén M, et al. Women with polycystic ovary syndrome are often depressed or anxious – A case control study. Psychoneuroendocrinology. 2008;33:1132–8. - PubMed
    1. Fauser BC. Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. Consensus on women's health aspects of polycystic ovary syndrome (PCOS) Hum Reprod. 2012;27:14–24. - PubMed
    1. Hussain A, Chandel RK, Ganie MA, Dar MA, Rather YH, Wani ZA, et al. Prevalence of psychiatric disorders in patients with a diagnosis of polycystic ovary syndrome in Kashmir. Indian J Psychol Med. 2015;37:66–70. - PMC - PubMed

LinkOut - more resources