Case Report of an Extensively Drug-Resistant Klebsiella pneumoniae Infection With Genomic Characterization of the Strain and Review of Similar Cases in the United States
- PMID: 29876363
- PMCID: PMC5961207
- DOI: 10.1093/ofid/ofy074
Case Report of an Extensively Drug-Resistant Klebsiella pneumoniae Infection With Genomic Characterization of the Strain and Review of Similar Cases in the United States
Abstract
Reports of extensively drug-resistant and pan-drug-resistant Klebsiella pneumoniae (XDR-KP and PDR-KP) cases are increasing worldwide. Here, we report a case of XDR-KP with an in-depth molecular characterization of resistance genes using whole-genome sequencing, and we review all cases of XDR-KP and PDR-KP reported in the United States to date.
Keywords: Klebsiella pneumoniae; antibiotic resistance; extensively drug-resistant; resistance genes.
References
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- Bathoorn E, Tsioutis C, da Silva Voorham JM et al. . Emergence of pan-resistance in KPC-2 carbapenemase-producing Klebsiella pneumoniae in Crete, Greece: a close call. J Antimicrob Chemother 2016; 71:1207–12. - PubMed
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