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Comparative Study
. 1985 Jan 25;13(2):617-30.
doi: 10.1093/nar/13.2.617.

Characterization of a mouse somatic cytochrome c gene and three cytochrome c pseudogenes

K J Limbach, R Wu
Free PMC article
Comparative Study

Characterization of a mouse somatic cytochrome c gene and three cytochrome c pseudogenes

K J Limbach et al. Nucleic Acids Res. .
Free PMC article

Abstract

Mouse contains two functional, but differentially expressed, cytochrome c genes. One of these genes is expressed in all somatic tissues so far examined. The other gene is expressed only in testis and is assumed to be spermatogenesis-specific. The nucleotide sequence of four mouse cytochrome c-like genes has been determined. One of these genes (MC1) contains an intron and encodes a polypeptide sequence identical to the published mouse somatic cytochrome c amino acid sequence. The other three genes can not properly encode a mouse cytochrome c protein and appear to be pseudogenes which have arisen via an insertion into the mouse genome of a cDNA copy of a cytochrome c mRNA molecule.

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