Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Nov 23:28:260.
doi: 10.11604/pamj.2017.28.260.10463. eCollection 2017.

[Seroprevalence of cysticercosis and associated risk factors in a group of patients examined at the Regional Referral Hospital in Antsirabe]

[Article in French]
Norosoa Julie Zafindraibe  1   2 , Jeannine Ralalarinivo  3 , Andriamiarimbola Irène Rakotoniaina  1   2 , Muriel Nirina Maeder  1   4 , Mala Rakoto Andrianarivelo  1 , Bénedicte Contamin  1   4 , Alain Michault  5 , Andry Rasamindrakotroka  2
Affiliations

[Seroprevalence of cysticercosis and associated risk factors in a group of patients examined at the Regional Referral Hospital in Antsirabe]

[Article in French]
Norosoa Julie Zafindraibe et al. Pan Afr Med J. .

Abstract
in English, French

Introduction: In Madagascar, cysticercosis, a disease caused by Taenia Solium's larval form, is a public health problem. In 2003, the seroprevalence of cysticercosis ranged between 7% and 21% with a higher rate in the central regions of the island. However, epidemiological data on human cysticercosis have been limited over the last dozen years. The objective of our study aimed to determine the seroprevalence of cysticercosis Western blot as well as its associated risk factors in patients from the region of Vakinankaratra with clinical suspicion.

Methods: We conducted a cross-sectional, descriptive study at the Regional Referral Hospital in Antsirabe over a period of 6 months. All the patients included in the study answered a clinic questionnaire collecting their socio-demographic and cultural features as well as their dietary habits and their clinical symptoms.

Results: The seroprevalence of cysticercosis in the study population was 14.8% (35/237). These rates did not differ significantly according to sex, age, pork consumption or meat preparation (p > 0.05). However, a significant difference (p < 0.05) was observed among patients with subcutaneous nodules or positive for cysticercosis.

Conclusion: In our study, the high index of exposure to Taenia solium justifies the strengthening of control and prevention measures already set up in our country.

Introduction: A Madagascar, la cysticercose, maladie causée par la forme larvaire de Taenia solium, demeure un problème de santé publique. En 2003, la séroprévalence de la cysticercose variait entre 7% et 21% avec un taux plus élevé dans les régions centrales de l’île. Toutefois, depuis une dizaine d’année, les données épidémiologiques concernant la cysticercose humaine restent limitées. Notre étude a pour objectif de déterminer, chez les patients issus de la région de Vakinankaratra et qui sont suspects cliniquement, la séroprévalence de la cysticercose par Western blot ainsi que les facteurs de risque associés.

Méthodes: Il s’agit d’une étude descriptive transversale menée sur une période de 6 mois au sein du Centre Hospitalier Régional de Référence d’Antsirabe. Tous les patients inclus dans l’étude ont répondu à un questionnaire clinique recueillant leurs caractéristiques sociodémographiques et culturelles ainsi que leurs habitudes alimentaires et leurs symptômes cliniques.

Résultats: La séroprévalence de la cysticercose retrouvée dans la population d’étude était de 14,8% (35/237). Ce taux ne diffère pas significativement selon le sexe, l’âge, la consommation de viande de porc ou le mode de préparation de la viande (p > 0,05). Par contre, une différence significative (p < 0,05) a été observée chez les sujets présentant des nodules sous-cutanés ou un résultat de cysticercose antérieur positif.

Conclusion: L’index élevé d’exposition à Taenia solium retrouvé dans notre étude justifie le renforcement des mesures de contrôle et de prévention déjà implantés dans le pays.

Keywords: Madagascar; Seroprevalence; Taenia solium; Western blot; cysticercosis.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Sciutto E, Fragoso G, Fleury A, Laclette JP, Sotelo J, Aluja A, Vargas L, Larralde C. Taenia solium disease in humans and pigs: an ancient parasitosis disease rooted in developing countries and emerging as a major health problem of global dimensions. Microbes Infect. 2000 Dec;2(15):1875–90. - PubMed
    1. Schantz PM, Wilkins PP, Tsang VCW. In: Immigrants, imaging and immunoblots: the emergence of neurocysticercosis as a signi?cant public health problem. Scheld W.M, Craig WA, Hughes J.M, editors. Washington DC.: Emerging Infections ASM press; 1998. pp. 213–242.
    1. Fan PC, Chung WC. Taenia saginata asiatica: epidemiology, infection, immunological and molecular studies. J Microbiol Immunol Infect. 1998 Jun;31(2):84–9. - PubMed
    1. Maguire JH. Tapeworms and seizures treatment and prevention. N Engl J Med. 2004 Jan 15;350(3):215–7. - PubMed
    1. O’Neal SE, Townes JM, Wilkins PP, Noh JC, Lee D, Rodriguez S, Garcia HH, Stauffer WM. Seroprevalence of antibodies against Taenia solium Cysticerci among refugees resettled in United States. Emerg Infect Dis. 2012 Mar;18(3):431–438. - PMC - PubMed

MeSH terms

LinkOut - more resources