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Comment
. 2018 Jun 7;70(5):763-764.
doi: 10.1016/j.molcel.2018.05.029. Epub 2018 Jun 7.

Stabbed while Sleeping: Synthetic Retinoid Antibiotics Kill Bacterial Persister Cells

Maarten Fauvart  1 , Bram Van den Bergh  2 , Jan Michiels  3
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Stabbed while Sleeping: Synthetic Retinoid Antibiotics Kill Bacterial Persister Cells

Maarten Fauvart et al. Mol Cell. .
Free article

Abstract

Antibiotic-tolerant persister cells are difficult to eradicate by conventional classes of antibiotics. Kim and colleagues have discovered a new class of synthetic retinoid antibiotics that kill Staphylococcus aureus persisters by disrupting their cytoplasmic membrane.

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