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Editorial
. 2018 Jul;29(7):1791-1792.
doi: 10.1681/ASN.2018050491. Epub 2018 Jun 8.

Transformation in Immunosuppression: Are We Ready for it?

Amtul Aala  1 , Daniel C Brennan  2
Affiliations
Editorial

Transformation in Immunosuppression: Are We Ready for it?

Amtul Aala et al. J Am Soc Nephrol. 2018 Jul.
No abstract available

Keywords: randomized controlled trials; tacrolimus; transplantation.

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Comment on

  • Everolimus with Reduced Calcineurin Inhibitor Exposure in Renal Transplantation.
    Pascual J, Berger SP, Witzke O, Tedesco H, Mulgaonkar S, Qazi Y, Chadban S, Oppenheimer F, Sommerer C, Oberbauer R, Watarai Y, Legendre C, Citterio F, Henry M, Srinivas TR, Luo WL, Marti A, Bernhardt P, Vincenti F; TRANSFORM Investigators. Pascual J, et al. J Am Soc Nephrol. 2018 Jul;29(7):1979-1991. doi: 10.1681/ASN.2018010009. Epub 2018 May 11. J Am Soc Nephrol. 2018. PMID: 29752413 Free PMC article. Clinical Trial.

References

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    1. Hart A, Smith JM, Skeans MA, Gustafson SK, Wilk AR, Robinson A, et al. : OPTN/SRTR 2016 annual data report: Kidney. Am J Transplant 18[Suppl 1]: 18–113, 2018 - PMC - PubMed
    1. Halloran PF, Chang J, Famulski K, Hidalgo LG, Salazar ID, Merino Lopez M, et al. : Disappearance of T cell-mediated rejection despite continued antibody-mediated rejection in late kidney transplant recipients. J Am Soc Nephrol 26: 1711–1720, 2015 - PMC - PubMed
    1. Einecke G, Sis B, Reeve J, Mengel M, Campbell PM, Hidalgo LG, et al. : Antibody-mediated microcirculation injury is the major cause of late kidney transplant failure. Am J Transplant 9: 2520–2531, 2009 - PubMed
    1. Nankivell BJ, PʼNg CH, OʼConnell PJ, Chapman JR: Calcineurin inhibitor nephrotoxicity through the lens of longitudinal histology: Comparison of cyclosporine and tacrolimus eras. Transplantation 100: 1723–1731, 2016 - PubMed