Iodide accumulation into thyroid Golgi vesicles
- PMID: 2988810
- DOI: 10.1002/cbf.290030106
Iodide accumulation into thyroid Golgi vesicles
Abstract
Pig thyroid Golgi vesicles incubated in a suitable medium were able to concentrate iodide from the medium. This trapping required the integrity of the vesicles, was time- and temperature-dependent, and was inhibited by a competitive inhibitor of iodide active transport (perchlorate), suggesting a facilitated transport mechanism.
Similar articles
-
Thyroid-stimulating hormone increases active transport of perchlorate into thyroid cells.Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E802-6. doi: 10.1152/ajpendo.00013.2008. Epub 2008 Feb 26. Am J Physiol Endocrinol Metab. 2008. PMID: 18303123
-
Evidence for competitive inhibition of iodide uptake by perchlorate and translocation of perchlorate into the thyroid.Int J Toxicol. 2004 Jan-Feb;23(1):17-23. doi: 10.1080/10915810490275044. Int J Toxicol. 2004. PMID: 15162843 Review.
-
Demonstration of iodide transport defect but normal iodide organification in nonfunctioning nodules of human thyroid glands.J Clin Invest. 1973 Oct;52(10):2404-10. doi: 10.1172/JCI107430. J Clin Invest. 1973. PMID: 4353998 Free PMC article.
-
Perchlorate and the thyroid gland.Pharmacol Rev. 1998 Mar;50(1):89-105. Pharmacol Rev. 1998. PMID: 9549759 Review.
-
Monoiodotyrosine formation during thyroglobulin processing in Golgi vesicles.Cell Biochem Funct. 1988 Jul;6(3):149-53. doi: 10.1002/cbf.290060302. Cell Biochem Funct. 1988. PMID: 3409477
Cited by
-
Lymphoma-on-chip model reveals that lymph node stromal cells promote diffuse large B-cell lymphoma survival and migration.Mater Today Bio. 2025 Feb 7;31:101544. doi: 10.1016/j.mtbio.2025.101544. eCollection 2025 Apr. Mater Today Bio. 2025. PMID: 40061210 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources