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. 1985 Jun;34(6):617-9.
doi: 10.2337/diab.34.6.617.

"Cytoplasmic" islet cell antibodies. Evidence that the target antigen is a sialoglycoconjugate

R C Nayak, M A Omar, A Rabizadeh, S Srikanta, G S Eisenbarth

"Cytoplasmic" islet cell antibodies. Evidence that the target antigen is a sialoglycoconjugate

R C Nayak et al. Diabetes. 1985 Jun.

Abstract

We have biochemically treated (periodate, borohydride, neuraminidase, organic solvents) frozen sections of human pancreas and studied the reactivity of islet-cell-antibody-positive human sera and monoclonal antibodies. The autoantigen of pancreatic sections has the properties of sialic acid containing glycolipid.

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