Drug treatment

Abstract

There are no approved disease-modifying therapies for any of the inherited cerebellar ataxias. Drug treatment in childhood ataxia is still very limited. Effective treatments are available for only a few rare metabolic hereditary disorders. Symptomatic management of associated tremor, spasticity, dystonia, or chorea can follow the medication recommendations in general usage. The foundation of management of cerebellar ataxia in adults or children remains rehabilitation.

Keywords: acetazolamide; acetylleucine; adult; amantadine; aminopyridine; buspirone; cerebellar ataxia; childhood; deferiprone; idebenone; riluzole; thyrotropin-releasing hormone; varenicline.