Building Capacity for a Global Genome Editing Observatory: Institutional Design

Krishanu Saha¹, J Benjamin Hurlbut², Sheila Jasanoff³, Aziza Ahmed⁴, Anthony Appiah⁵, Elizabeth Bartholet⁶, Françoise Baylis⁷, Gaymon Bennett⁸, George Church⁹, I Glenn Cohen¹⁰, George Daley¹¹, Kevin Finneran¹², William Hurlbut¹³, Rudolf Jaenisch¹⁴, Laurence Lwoff¹⁵, John Paul Kimes¹⁶, Peter Mills¹⁷, Jacob Moses¹⁸, Buhm Soon Park¹⁹, Erik Parens²⁰, Rachel Salzman²¹, Abha Saxena²², Hilton Simmet²³, Tania Simoncelli²⁴, O Carter Snead²⁵, Kaushik Sunder Rajan²⁶, Robert D Truog²⁷, Patricia Williams²⁸, Christiane Woopen²⁹

Affiliations

¹ University of Wisconsin-Madison, Madison, WI, USA; Website: https://sahalab.bme.wisc.edu/; Note: The views expressed in this article are those of the authors and do not represent the official policies or positions of the organizations with which they are affiliated. Author affiliations are as of April, 2017. Electronic address: ksaha@wisc.edu.
² Arizona State University, Tempe, AZ, USA. Electronic address: bhurlbut@asu.edu.
³ Harvard Kennedy School, Cambridge, MA, USA; Website: http://sts.hks.harvard.edu/. Electronic address: http://www.twitter.com/SJasanoff.
⁴ Northeastern University School of Law, Boston, MA, USA. Electronic address: http://www.twitter.com/AzizaAhmed.
⁵ New York University, New York, NY, USA. Electronic address: http://www.twitter.com/KAnthonyAppiah.
⁶ Harvard Law School, Cambridge, MA, USA.
⁷ Dalhousie University, Halifax, NS, Canada. Electronic address: http://www.twitter.com/FrancoiseBaylis.
⁸ Arizona State University, Tempe, AZ, USA.
⁹ Harvard Medical School, Boston, MA, USA. Electronic address: http://www.twitter.com/geochurch.
¹⁰ Harvard Law School, Cambridge, MA, USA. Electronic address: http://www.twitter.com/CohenProf.
¹¹ Harvard Medical School, Boston, MA, USA. Electronic address: http://www.twitter.com/G_Q_Daley.
¹² National Academies of Science, Engineering, and Medicine, Washington DC, USA.
¹³ Stanford University School of Medicine, Stanford, CA, USA.
¹⁴ Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Massachusetts Institute of Technology, Cambridge, MA, USA.
¹⁵ Council of Europe, Strasbourg, France.
¹⁶ University of Notre Dame, Notre Dame, IN, USA.
¹⁷ Nuffield Council on Bioethics, London, UK. Electronic address: http://www.twitter.com/PeterFRMills.
¹⁸ Harvard University, Cambridge, MA, USA.
¹⁹ Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
²⁰ The Hastings Center, Garrison, NY, USA.
²¹ ALD Connect, Boston, MA, USA.
²² World Health Organization, Geneva, Switzerland.
²³ Harvard Kennedy School, Cambridge, MA, USA.
²⁴ Broad Institute, Cambridge, MA, USA.
²⁵ University of Notre Dame Law School, Notre Dame, IN, USA. Electronic address: http://www.twitter.com/cartersnead.
²⁶ University of Chicago, Chicago, IL, USA.
²⁷ Harvard Medical School, Boston, MA, USA; Boston Children's Hospital, Boston, MA, USA.
²⁸ Columbia Law School, New York, NY, USA.
²⁹ Research Unit Ethics and CERES, University of Cologne. Electronic address: http://www.twitter.com/CWoopen.

PMID: 29891181
PMCID: PMC6529360
DOI: 10.1016/j.tibtech.2018.04.008

Building Capacity for a Global Genome Editing Observatory: Institutional Design

Krishanu Saha et al. Trends Biotechnol. 2018 Aug.

. 2018 Aug;36(8):741-743.

doi: 10.1016/j.tibtech.2018.04.008. Epub 2018 Jun 8.

Authors

Affiliations

¹ University of Wisconsin-Madison, Madison, WI, USA; Website: https://sahalab.bme.wisc.edu/; Note: The views expressed in this article are those of the authors and do not represent the official policies or positions of the organizations with which they are affiliated. Author affiliations are as of April, 2017. Electronic address: ksaha@wisc.edu.
² Arizona State University, Tempe, AZ, USA. Electronic address: bhurlbut@asu.edu.
³ Harvard Kennedy School, Cambridge, MA, USA; Website: http://sts.hks.harvard.edu/. Electronic address: http://www.twitter.com/SJasanoff.
⁴ Northeastern University School of Law, Boston, MA, USA. Electronic address: http://www.twitter.com/AzizaAhmed.
⁵ New York University, New York, NY, USA. Electronic address: http://www.twitter.com/KAnthonyAppiah.
⁶ Harvard Law School, Cambridge, MA, USA.
⁷ Dalhousie University, Halifax, NS, Canada. Electronic address: http://www.twitter.com/FrancoiseBaylis.
⁸ Arizona State University, Tempe, AZ, USA.
⁹ Harvard Medical School, Boston, MA, USA. Electronic address: http://www.twitter.com/geochurch.
¹⁰ Harvard Law School, Cambridge, MA, USA. Electronic address: http://www.twitter.com/CohenProf.
¹¹ Harvard Medical School, Boston, MA, USA. Electronic address: http://www.twitter.com/G_Q_Daley.
¹² National Academies of Science, Engineering, and Medicine, Washington DC, USA.
¹³ Stanford University School of Medicine, Stanford, CA, USA.
¹⁴ Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Massachusetts Institute of Technology, Cambridge, MA, USA.
¹⁵ Council of Europe, Strasbourg, France.
¹⁶ University of Notre Dame, Notre Dame, IN, USA.
¹⁷ Nuffield Council on Bioethics, London, UK. Electronic address: http://www.twitter.com/PeterFRMills.
¹⁸ Harvard University, Cambridge, MA, USA.
¹⁹ Korea Advanced Institute of Science and Technology, Daejeon, South Korea.
²⁰ The Hastings Center, Garrison, NY, USA.
²¹ ALD Connect, Boston, MA, USA.
²² World Health Organization, Geneva, Switzerland.
²³ Harvard Kennedy School, Cambridge, MA, USA.
²⁴ Broad Institute, Cambridge, MA, USA.
²⁵ University of Notre Dame Law School, Notre Dame, IN, USA. Electronic address: http://www.twitter.com/cartersnead.
²⁶ University of Chicago, Chicago, IL, USA.
²⁷ Harvard Medical School, Boston, MA, USA; Boston Children's Hospital, Boston, MA, USA.
²⁸ Columbia Law School, New York, NY, USA.
²⁹ Research Unit Ethics and CERES, University of Cologne. Electronic address: http://www.twitter.com/CWoopen.

PMID: 29891181
PMCID: PMC6529360
DOI: 10.1016/j.tibtech.2018.04.008

Abstract

A new infrastructure is urgently needed at the global level to facilitate exchange on key issues concerning genome editing. We advocate the establishment of a global observatory to serve as a center for international, interdisciplinary, and cosmopolitan reflection. This article is the second of a two-part series.

Keywords: CRISPR; bioethics; ethics; genome editing; science and technology studies; science policy.

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Comment in

We Must Not Avoid Germline Gene Editing to Preserve Social Values: A Response to Saha et al.
de Miguel Beriain I. de Miguel Beriain I. Trends Biotechnol. 2018 Dec;36(12):1205-1206. doi: 10.1016/j.tibtech.2018.07.010. Epub 2018 Aug 10. Trends Biotechnol. 2018. PMID: 30104011
Response to Beriain.
Saha K, Hurlbut JB, Jasanoff S. Saha K, et al. Trends Biotechnol. 2018 Dec;36(12):1206-1207. doi: 10.1016/j.tibtech.2018.08.004. Epub 2018 Sep 14. Trends Biotechnol. 2018. PMID: 30224226

References

1. Jasanoff S, and Hurlbut JB. “A global observatory for gene editing.” Nature 555, no. 7697 (2018): 435. - PubMed
1. Jasanoff Sheila, Hurlbut J. Benjamin, and Saha Krishanu. “CRISPR Democracy: Gene Editing and the Need for Inclusive Deliberation ∣ Issues in Science and Technology.” Issues in Science and Technology, Fall 2015.
1. Jasanoff Sheila. Designs on Nature: Science and Democracy in Europe and the United States. Princeton, N.J: Princeton University Press, 2005.
1. Ma H, Marti-Gutierrez N, Park SW, Wu J, Lee Y, Suzuki K, Koski A, Ji D, Hayama T, Ahmed R, et al. (2017). Nature 548, 413–419. - PubMed
1. National Academies of Sciences, Engineering, and Medicine. (2017) https://www.nap.edu/catalog/24623/human-genome-editing-science-ethics-an...

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Building Capacity for a Global Genome Editing Observatory: Institutional Design

Affiliations

Building Capacity for a Global Genome Editing Observatory: Institutional Design

Authors

Affiliations

Abstract

Comment in

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources