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. 2018 May 10;33(24):e169.
doi: 10.3346/jkms.2018.33.e169. eCollection 2018 Jun 11.

Correlation between Pneumonia Severity and Pulmonary Complications in Middle East Respiratory Syndrome

Wan Beom Park  1 , Kang Il Jun  1 , Gayeon Kim  2 , Jae-Phil Choi  3 , Ji-Young Rhee  4 , Shinhyea Cheon  5 , Chang Hyun Lee  6   7 , Jun-Sun Park  8 , Yeonjae Kim  2 , Joon-Sung Joh  9 , Bum Sik Chin  2 , Pyeong Gyun Choe  1 , Ji Hwan Bang  1 , Sang-Won Park  1 , Nam Joong Kim  1 , Dong-Gyun Lim  2 , Yeon-Sook Kim  5 , Myoung-Don Oh  1 , Hyoung-Shik Shin  2
Affiliations

Correlation between Pneumonia Severity and Pulmonary Complications in Middle East Respiratory Syndrome

Wan Beom Park et al. J Korean Med Sci. .

Abstract

This nationwide, prospective cohort study evaluated pulmonary function and radiological sequelae according to infection severity in 73 survivors from the 2015 Middle East respiratory syndrome (MERS) outbreak in Korea. Patients with severe pneumonia in MERS-coronavirus infection had more impaired pulmonary function than those with no or mild pneumonia at the 1-year follow-up, which was compatible with the radiological sequelae. Severe pneumonia significantly impairs pulmonary function and makes long radiological sequelae in MERS.

Keywords: Complication; Coronavirus; MERS; Outbreak.

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Conflict of interest statement

Disclosure: The authors have no potential conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1. Comparison of pulmonary function in patients with no or mild pneumonia and patients with severe pneumonia. (A) FVC. (B) FEV1. (C) DLCO. P values were adjusted for age, sex, underlying lung disease, and smoking. Whiskers indicate minimum and maximum values.
FVC = forced volume vital capacity, FEV1 = forced expiratory volume in 1 second, DLCO = diffusing capacity, MERS = Middle East respiratory syndrome.
See this image and copyright information in PMC

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