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. 1985 Jul 1;162(1):363-8.
doi: 10.1084/jem.162.1.363.

Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells

W C Greene, R J Robb, P B Svetlik, C M Rusk, J M Depper, W J Leonard

Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells

W C Greene et al. J Exp Med. .

Abstract

Human interleukin 2 (IL-2) receptor cDNA derived from HUT 102B2 cells was stably expressed in murine L cells. These L cell transfectants (a) displayed surface receptors of the aberrant size of the IL-2 receptors on HUT 102B2 cells, (b) did not respond to exogenous IL-2 with augmented proliferation, and (c) expressed low affinity but not high affinity receptors for IL-2.

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