Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jun 13;18(1):720.
doi: 10.1186/s12889-018-5557-8.

Association between sleep duration and metabolic syndrome: a cross-sectional study

Claire E Kim  1   2 , Sangah Shin  3 , Hwi-Won Lee  1   2 , Jiyeon Lim  1 , Jong-Koo Lee  4   5 , Aesun Shin  1 , Daehee Kang  6   7   8
Affiliations

Association between sleep duration and metabolic syndrome: a cross-sectional study

Claire E Kim et al. BMC Public Health. .

Abstract

Background: Both short and long sleep duration have been consistently studied as a risk factor for obesity, hyperglycemia and hypertension. In this cross-sectional study, we provide an updated analysis of the Health Examinees (HEXA) study on the association between sleep duration and metabolic syndrome (MetS) occurrence among Koreans age 40-69 year olds.

Methods: A total of 133,608 subjects (44,930 men, 88,678 women) were enrolled in the HEXA study 2004-2013. Sleep duration was categorized into 4 sleep categories (< 6 h, 6 to < 8 h, 8 to < 10 h, ≥10 h). MetS criterion was based on the National Cholesterol Education Program, Adult Treatment Panel III. Logistic regression was used to calculate adjusted odds ratios (ORs) and 95% confidence intervals (CIs).

Results: Compared with individuals sleeping 6 to < 8 h per day, less than 6 h of sleep was associated with MetS (multivariable adjusted OR: 1.12, 95% CI: 1.05-1.19) and elevated waist circumference (1.15, 1.08-1.23) among men; with elevated waist circumference (1.09, 1.04-1.14) among women. Greater than 10 h of sleep was associated with MetS (1.28, 1.08-1.50) and elevated triglycerides (1.33, 1.14-1.56) among men; with MetS (1.40, 1.24-1.58), elevated waist circumference (1.14, 1.02-1.27), elevated triglycerides (1.41, 1.25-1.58), reduced high-density lipoprotein cholesterol (HDL-C) (1.24, 1.12-1.38), and elevated fasting glucose (1.39, 1.23-1.57) among women.

Conclusions: Less than 6 h of sleep is associated with elevated waist circumference among both men and women and with MetS among men only. Greater than 10 h of sleep is associated with MetS and elevated triglycerides among both men and women and with elevated waist circumference, reduced HDL-C, and elevated fasting glucose among women only.

Keywords: Diabetes; Epidemiology; Metabolic disorder; Metabolic syndrome; Sleep duration.

PubMed Disclaimer

Conflict of interest statement

Ethics approval and consent to participate

The HEXA study protocol was approved by the Institutional Review Board (IRB) of the Seoul National University Hospital, Seoul, Korea (IRB number 0608–018- 179) and the Korea National Institute of Health (IRB number 2014–08-02-3C-A). All study participants gave written informed consent prior to entering the study.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Flow diagram of analytical sample: the HEXA study (2004-2013)
See this image and copyright information in PMC

References

    1. Office of Disease Prevention and Health Promotion . Healthy People 2020: Sleep Health. 2017.
    1. National Sleep Foundation . National Sleep Foudnation Recommends new Sleep Times. For Immediate & Release. 2015.
    1. National Sleep Foundation. Sleep Hygiene. Sleep Topics. 2017;
    1. Kim K, Shin D, Jung GU, Lee D, Park SM. Association between sleep duration, fat mass, lean mass and obesity in Korean adults: the fourth and fifth Korea National Health and nutrition examination surveys. J Sleep Res. 2017;26(4):453–460. doi: 10.1111/jsr.12504. - DOI - PubMed
    1. Magee CA, Kritharides L, Attia J, McElduff P, Banks E. Short and long sleep duration are associated with prevalent cardiovascular disease in Australian adults. J Sleep Res. 2012;21(4):441–447. doi: 10.1111/j.1365-2869.2011.00993.x. - DOI - PubMed

Substances