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. 2018 May;76(5):296-301.
doi: 10.1590/0004-282X20180036.

Suicidal ideation, anxiety, and depression in patients with multiple sclerosis

Carlos Bernardo Tauil  1   2   3 , Talyta Cortez Grippe  1   3 , Ronaldo Maciel Dias  1 , Rafael Paternò Castello Dias-Carneiro  4 , Narel Moita Carneiro  1 , Ana Carolina Rodrigues Aguilar  1 , Flávia Martins da Silva  1 , Felipe Bezerra  2 , Leonardo Kenzo de Almeida  2 , Vitoria Lana Massarente  4 , Elaine de Carvalho Giovannelli  4 , Charles Peter Tilbery  4 , Carlos Otávio Brandão  5 , Leonilda Maria B Santos  5 , Leopoldo Dos Santos-Neto  3
Affiliations
Free article

Suicidal ideation, anxiety, and depression in patients with multiple sclerosis

Carlos Bernardo Tauil et al. Arq Neuropsiquiatr. 2018 May.
Free article

Abstract

Introduction: Psychiatric disorders frequently occur in patients with multiple sclerosis (MS); however, limited reports are available on these comorbidities. We aimed to investigate the relationships among MS, anxiety, depression, and suicidal ideation.

Methods: One hundred and thirty two patients with relapsing-remitting MS were evaluated using the Expanded Disability Status Scale, Beck Depression Inventory-II (BDI-II), Beck Scale for Suicide Ideation (BSI), and Hospital Anxiety and Depression Scale.

Results: A hierarchical regression analysis was performed to evaluate the variables. The regression equation significantly predicted the BSI score (R2 = 0.306; adjusted R2 = 0.273; F (9, 125) = 9.18; p < 0.0005), and the BDI-II score was the only variable that contributed significantly to this model (p < 0.0005).

Conclusions: A high prevalence of depression and anxiety, and a higher rate of suicidal ideation were identified in MS patients compared to the general population. The presence of depressive symptoms appeared to have a direct influence on the risk of suicide.

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