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. 2018 Jun 7;16(2):eAO4248.
doi: 10.1590/S1679-45082018AO4248.

Oral and oropharyngeal cancer: epidemiology and survival analysis

[Article in English, Portuguese]
Juliana da Silva Moro  1 , Marília Cunha Maroneze  1 , Thiago Machado Ardenghi  1 , Luisa Machado Barin  1 , Cristiane Cademartori Danesi  1
Affiliations

Oral and oropharyngeal cancer: epidemiology and survival analysis

[Article in English, Portuguese]
Juliana da Silva Moro et al. Einstein (Sao Paulo). .

Abstract
in English, Portuguese

Objective: To evaluate the epidemiological profile and survival rate of oral and oropharyngeal cancer patients seen at a university hospital.

Methods: A cross-sectional study was carried out by means of the pathological reports of patients with oral and oropharyngeal cancer, seen at a university hospital of the Southern Region, between January 2004 and December 2014. Information was collected on patients and tumors. The mortality rate was gathered from the patient death registry in the Mortality Information System. Data were analyzed using the Kaplan-Meier survival curve and the log-rank test to compare variables.

Results: The 5- and 10-year survival rates were 42% and 38%, respectively. The anatomical location had a significant association with survival rate (p=0.001), with the rates were better in the lips (p=0.04), and worse in the oropharynx (p=0.03). There were no statistically significant differences between survival rates according to age, sex, ethnicity, schooling level and histologic grade.

Conclusion: The survival rates of oral and oropharyngeal cancer were and associated with the anatomical site of the tumor.

Objetivo: Avaliar o perfil epidemiológico e a taxa de sobrevida do câncer de boca e orofaringe de pacientes atendidos em um hospital universitário.

Métodos: Foi realizado um estudo transversal por meio dos laudos anatomopatológicos dos pacientes com câncer de boca e orofaringe atendidos em um hospital universitário, na Região Sul, entre janeiro de 2004 a dezembro de 2014. A partir destes laudos, foram coletadas informações sobre o paciente e o tumor. A taxa de mortalidade foi obtida do registro de óbitos dos pacientes no Sistema de Informações sobre Mortalidade. Os dados foram analisados utilizando a curva de sobrevida pelo método de Kaplan-Meier e o teste de log-rank para a comparação das variáveis.

Resultados: As taxas de sobrevida em 5 e 10 anos foram 42% e 38%, respectivamente. A localização anatômica apresentou associação significativa com a taxa de sobrevida (p=0,001), sendo que, em lábio, os índices foram melhores (p=0,04) e, em orofaringe, piores (p=0,03). Não houve diferenças estatisticamente significantes entre as taxas de sobrevida de acordo com idade, sexo, etnia, nível educacional e grau histológico.

Conclusão: As taxas de sobrevida do câncer de boca e orofaringe foram baixas e associadas à localização anatômica do tumor.

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Conflict of interest statement

Conflict of interest:

none.

Figures

Figure 1
Figure 1. Kaplan-Meier survival analysis for oral and oropharyngeal cancer
Figure 2
Figure 2. Kaplan-Meier survival analysis for site of oral and oropharyngeal cancer
See this image and copyright information in PMC

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