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Case Reports
. 1985 Jul;32(1):155-60.

Human T-cell leukemia/lymphoma syndrome

E S Christian, J B Craig, H B Muss, R M Christian, R D Michaelson
  • PMID: 2990186
Case Reports

Human T-cell leukemia/lymphoma syndrome

E S Christian et al. Am Fam Physician. 1985 Jul.

Abstract

This syndrome should be suspected in patients with clinical features of lymphadenopathy, hepatosplenomegaly, hypercalcemia, bone lesions and circulating lymphocytes with pleomorphic nuclei. Most biopsy material has morphologic characteristics of intermediate or high-grade non-Hodgkins lymphoma. Antibody titers to human T-lymphotropic virus type I confirm the diagnosis. Treatment with combination chemotherapy results in remission for most patients, but duration of response is usually short.

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