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. 1985:30:469-87.
doi: 10.1007/978-1-4613-2447-8_34.

Mechanisms essential for stable inheritance of mini-F plasmid

S Hiraga, T Ogura, H Mori, M Tanaka

Mechanisms essential for stable inheritance of mini-F plasmid

S Hiraga et al. Basic Life Sci. 1985.

Abstract

The F plasmid has its own partition mechanism and ccd mechanism (coupled cell division), besides its own replication mechanism, in order to be stably inherited into daughter cells through cell division. These 3 mechanisms are independent of one another. Therefore, when a DNA segment essential and sufficient for a mechanism is jointed to other heterologous plasmids, the segment is also functional. Most of natural low copy number plasmids might also have their own replication, partition, and ccd mechanisms. These 3 mechanisms may be fundamental to ensure stable inheritance for low copy-number replicons in prokaryotes.

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