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Review
. 2018 Nov;28(8):516-521.
doi: 10.1016/j.tcm.2018.05.001. Epub 2018 Jun 12.

Sudden death risk markers for patients with left ventricular ejection fractions greater than 40

Brian P Halliday  1 , Amrit S Lota  1 , Sanjay K Prasad  2
Affiliations
Free article
Review

Sudden death risk markers for patients with left ventricular ejection fractions greater than 40

Brian P Halliday et al. Trends Cardiovasc Med. 2018 Nov.
Free article

Abstract

The major burden of sudden cardiac death (SCD) in patients with heart disease occurs in those with a left ventricular ejection fraction > 40%. Although the annual risk of SCD may be lower in these patients compared to those with lower LVEF, their lifetime cumulative risk of SCD may be greater due to a better overall prognosis. It is plausible that those with LVEF > 40% who are at highest risk of life-threatening arrhythmia will benefit from implantable cardioverter defibrillators. Features that identify patients with a LVEF > 40% at high risk of SCD are urgently needed. We review existing studies examining SCD markers in this sub-group and discuss gaps in the current evidence base.

Keywords: LVEF; Risk factors; Sudden cardiac death.

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