Debate over the identity of an intestinal niche-cell population settled

Comment

Linda C Samuelson. Nature. 2018 Jun.

. 2018 Jun;558(7710):380-381.

doi: 10.1038/d41586-018-05281-z.

No abstract available

Keywords: Cell biology; Developmental biology; Stem cells.

Comment on

Subepithelial telocytes are an important source of Wnts that supports intestinal crypts.
Shoshkes-Carmel M, Wang YJ, Wangensteen KJ, Tóth B, Kondo A, Massasa EE, Itzkovitz S, Kaestner KH. Shoshkes-Carmel M, et al. Nature. 2018 May;557(7704):242-246. doi: 10.1038/s41586-018-0084-4. Epub 2018 May 2. Nature. 2018. PMID: 29720649 Free PMC article.
GLI1-expressing mesenchymal cells form the essential Wnt-secreting niche for colon stem cells.
Degirmenci B, Valenta T, Dimitrieva S, Hausmann G, Basler K. Degirmenci B, et al. Nature. 2018 Jun;558(7710):449-453. doi: 10.1038/s41586-018-0190-3. Epub 2018 Jun 6. Nature. 2018. PMID: 29875413