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. 2016 May 6;4(2):26.
doi: 10.3390/sports4020026.

The Effects of a Multi-Ingredient Performance Supplement on Hormonal Profiles and Body Composition in Male College Athletes

Matthew H Sharp  1 , Kevin A Shields  2 , Jacob T Rauch  3 , Ryan P Lowery  4 , Shane E Durkee  5 , Gabriel J Wilson  6 , Eduardo O De Souza  7
Affiliations

The Effects of a Multi-Ingredient Performance Supplement on Hormonal Profiles and Body Composition in Male College Athletes

Matthew H Sharp et al. Sports (Basel). .

Abstract

Periods of intense training can elicit an acute decline in performance and body composition associated with weakened hormone profiles. This study investigated the effects of a multi-ingredient performance supplement (MIPS) on body composition and hormone levels in college athletes following a six-week training protocol. Twenty male college athletes were equally assigned to MIPS and placebo (PLA) groups for supplementation (three pills, twice daily) in conjunction with resistance training and specialized sports training (e.g., nine total sessions/week) for six weeks. Dual Energy X-ray Absorptiometry determined body composition at weeks 0 and 6. Serum samples collected at weeks 0 and 6 determined free testosterone (FT), total testosterone (TT), IGF-1 and total estrogen (TE) levels. PLA experienced a significant decline in lean body mass (LBM) (-1.5 kg; p < 0.05) whereas the MIPS sustained LBM. The MIPS increased TT 21.9% (541.5 ± 48.7 to 639.1 ± 31.7) and increased FT 15.2% (13.28 ± 1.1 to 15.45 ± 1.3 ng/dL) (p < 0.05). Conversely, PLA decreased TT 7.9% (554.5 ± 43.3 to 497.2 ± 39.1 ng/dL), decreased FT 17.4% (13.41 ± 1.8 to 11.23 ± 2.55 ng/dL), and decreased FT:E 12.06% (p < 0.05). These findings suggest the MIPS can prevent decrements in LBM and anabolic hormone profiles during intense training periods.

Keywords: herbal ingredients; lean body mass; resistance training; testosterone.

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Conflict of interest statement

Matthew H. Sharp, Kevin A. Shields, Jacob T. Rauch, Ryan P. Lowery and Eduardo O. De Souza declare no conflicts of interest. These authors were in charge of designing and performing the study, as well as manuscript preparation. Shane E. Durkee and Gabriel J. Wilson work for Maximum Human Performance who sell the MIPS tested in this study. They were involved in writing the manuscript, but had no involvement in performing the study.

Figures

Figure 1
Figure 1
Body composition. (A) Group pre- and post-test lean body mass values; (B) Group pre- and post-testing fat mass values.
Figure 2
Figure 2
Measures of Plasma Total & Free Testosterone. (A) Group pre- and post-test total testosterone levels; (B) Group pre- and post-testing free testosterone levels.
Figure 3
Figure 3
Total Testosterone to Estrogen (TT:E) & Free Testosterone to Estrogen (FT:E) Ratios, (A) Group pre- and post-testing TT:E values; (B) Group pre- and post-testing FT:E values.
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