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. 2017 Aug 7;5(3):58.
doi: 10.3390/sports5030058.

Are We Compensating for the Lack of Physical Activity in Our Diabetic Patients with Treatment Intensification?

Maja Cigrovski Maja Cigrovski Berkovic  1 , Ines Bilic-Curcic  2 , Marina Gradiser  3 , Davorka Herman-Mahecic  4 , Vjekoslav Cigrovski  5 , Marul Ivandic  6
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Are We Compensating for the Lack of Physical Activity in Our Diabetic Patients with Treatment Intensification?

Maja Cigrovski Maja Cigrovski Berkovic et al. Sports (Basel). .

Abstract

Background: We studied the association between leisure time physical activity (LTPA) and glycemic control, body mass index (BMI), and hypoglycemic incidents in type 1 (T1DM) and type 2 diabetes patients (T2DM).

Methods: This is a cross-sectional study of 198 diabetic patients (60 with type 1 diabetes, 138 with type 2 diabetes). LTPA was assessed by a validated 12-month questionnaire. Patients were grouped as sedentary and moderately to vigorously active. Outcome measures were Hemoglobin A1c (HbA1c), BMI, and hypoglycemic episodes.

Results: LTPA effect on the HbA1c reduction was present in diabetes type 1 patients. Patients who were involved in the moderate to vigorous-intensity physical activity had a greater decrease in the HbA1c (p = 0.048) than patients with low physical activity (p = 0.085). Level of LTPA was neither associated with increased number of hypoglycemic episodes, nor BMI. After an average of 4 years of diabetes, the number of patients requiring more than one antidiabetic agent increased, although the observed difference did not correlate with LTPA level.

Conclusions: LTPA has an influence on the regulation of diabetes type 1, and intensification of medical treatment is compensating for the lack of lifestyle change-especially in type 2 diabetics.

Keywords: body mass index; diabetes mellitus; glycemic control; hypoglycemia; leisure time physical activity.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Treatment intensification during course of disease for patients with type 2 DM (n = 126); error bars represent 95% confidence interval. SU, sulphonylurea; DPP-4i, dipeptidyl peptidase-4 inhibitors; GLP-1 RA, glucagon-like peptide receptor agonist.
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References

    1. American Diabetes Association Diagnosis and classification of diabetes mellitus. Diabetes Care. 2014;37:S81–S90. doi: 10.2337/dc14-S081. - DOI - PubMed
    1. Defronzo R.A. Banting lecture. From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus. Diabetes. 2009;58:773–795. doi: 10.2337/db09-9028. - DOI - PMC - PubMed
    1. Brown J., Nichols G., Perry A. The burden of treatment failure in type 2 diabetes. Diabetes Care. 2004;75:1535–1540. doi: 10.2337/diacare.27.7.1535. - DOI - PubMed
    1. Khunti K., Wolden M.L., Thorsted B.L., Andersen M., Davies M.J. Clinical inertia in people with type 2 diabetes: A retrospective cohort study of more than 80,000 people. Diabetes Care. 2013;36:3411–3417. doi: 10.2337/dc13-0331. - DOI - PMC - PubMed
    1. International Diabetes Federation IDF Diabetes Atlas. [(accessed on 27 May 2016)];2013 Available online: www.idf.org/diabetesatlas.

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