Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985 Sep;55(3):710-20.
doi: 10.1128/JVI.55.3.710-720.1985.

Epstein-Barr virus-encoded protein found in plasma membranes of transformed cells

K P Mann, D Staunton, D A Thorley-Lawson

Epstein-Barr virus-encoded protein found in plasma membranes of transformed cells

K P Mann et al. J Virol. 1985 Sep.

Abstract

We have developed monoclonal antibodies to a 63,000-molecular-weight protein (p63) which is the product of the most abundant messenger RNA in Epstein-Barr virus-transformed cells and shown that the protein is associated specifically with plasma membranes. It was also found to be associated with the other membrane fractions and was found in all Epstein-Barr virus-transformed cells tested. In addition, p63 was present in virions, resulting in transient, early appearance in newly infected cells. Newly synthesized p63 was detected at the time cells underwent blast transformation (48 to 72 h postinfection). The possible role of this protein in transformation and as a target for cell-mediated cytotoxicity is discussed.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Int J Cancer. 1979 Sep 15;24(3):294-302 - PubMed
    1. J Virol. 1979 Jan;29(1):261-74 - PubMed
    1. Proc Natl Acad Sci U S A. 1984 Jan;81(1):43-7 - PubMed
    1. Virology. 1978 May 15;86(2):423-31 - PubMed
    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed

Publication types