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. 1985 Aug;134(2):280-3.
doi: 10.1016/s0022-5347(17)47123-0.

The use of collagenase in the treatment of Peyronie's disease

M K Gelbard, A Lindner, J J Kaufman

The use of collagenase in the treatment of Peyronie's disease

M K Gelbard et al. J Urol. 1985 Aug.

Abstract

Purified clostridial collagenase was administered intralesionally in 31 men with Peyronie's disease. Within 4 weeks of treatment 20 patients showed an objective improvement. Pain was eliminated in 13 of 14 patients with this complaint at presentation within the same 4-week period. The ability to have intercourse was restored in 3 of 4 patients with this problem. Except for a small corporeal rupture at the site of injection in 1 patient, no significant untoward effects were noted. During the mean 9.8-month followup 1 recurrence of bending was noted.

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