Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jul 1;7(7):giy072.
doi: 10.1093/gigascience/giy072.

YAMP: a containerized workflow enabling reproducibility in metagenomics research

Affiliations

YAMP: a containerized workflow enabling reproducibility in metagenomics research

Alessia Visconti et al. Gigascience. .

Abstract

YAMP ("Yet Another Metagenomics Pipeline") is a user-friendly workflow that enables the analysis of whole shotgun metagenomic data while using containerization to ensure computational reproducibility and facilitate collaborative research. YAMP can be executed on any UNIX-like system and offers seamless support for multiple job schedulers as well as for the Amazon AWS cloud. Although YAMP was developed to be ready to use by nonexperts, bioinformaticians will appreciate its flexibility, modularization, and simple customization.

PubMed Disclaimer

Figures

Figure 1:
Figure 1:
The YAMP workflow. White rectangles represent data to be provided as input, and blue rectangles those produced in output. Pentagons represent the analysis steps.
Figure 2:
Figure 2:
An excerpt from the YAMP execution log.
Figure 3:
Figure 3:
An example of the YAMP execution profile. YAMP returns the time spent during its complete execution and in each step, as well as the steps’ memory peaks.
Figure 4:
Figure 4:
Phylum-level relative abundances. Each vertical bar represents a sample. Phylum relative abundances were estimated by YAMP using MetaPhlAn2. Unspecified viral phyla are not shown.

Similar articles

Cited by

References

    1. Baker M. 1,500 scientists lift the lid on reproducibility. Nature News. 2016;533(7604):452. - PubMed
    1. Ioannidis JP, Allison DB, Ball CA, et al. Repeatability of published microarray gene expression analyses. Nat Genet. 2009;41(2):149–55. - PubMed
    1. Hothorn T, Leisch F. Case studies in reproducibility. Brief Bioinform. 2011;12(3):288–300. - PubMed
    1. Peng RD. Reproducible research in computational science. Science. 2011;334(6060):1226–7. - PMC - PubMed
    1. Gronenschild EH, Habets P, Jacobs HI, et al. The effects of FreeSurfer version, workstation type, and Macintosh operating system version on anatomical volume and cortical thickness measurements. PLoS One. 2012;7(6):e38234. - PMC - PubMed

Publication types

LinkOut - more resources