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Review
. 2018 Nov;1431(1):25-34.
doi: 10.1111/nyas.13872. Epub 2018 Jun 19.

Exposure to hypoglycemia and risk of stroke

Logan Smith  1   2 , Diya Chakraborty  1   2 , Pallab Bhattacharya  3   4 , Deepaneeta Sarmah  3 , Sebastian Koch  2 , Kunjan R Dave  1   2   5
Affiliations
Review

Exposure to hypoglycemia and risk of stroke

Logan Smith et al. Ann N Y Acad Sci. 2018 Nov.

Abstract

In the treatment of both type 1 and type 2 diabetes mellitus, maintaining a euglycemic state represents one of the key challenges. Improper dosing and administration of glucose-lowering drugs is associated with an increased risk of recurrent hypoglycemia episodes. In addition, the risk of adverse cardiovascular events in diabetic patients, particularly myocardial infarctions and strokes, is well established. Current research indicates a potential link between the baseline risk of cardio/cerebrovascular events in diabetic patients and exposure to hypoglycemia. In this review of the literature, we aim to determine if a relationship exists between recurrent hypoglycemia and adverse neurovascular events.

Keywords: cerebrovascular event; diabetes; hypoglycemia; stroke.

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Conflict of interest statement

Competing interests

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Schematic diagram summarizing procoagulant mechanisms activated by hypoglycemia.
See this image and copyright information in PMC

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