Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 May-Aug;11(2):214-216.
doi: 10.4103/apc.APC_174_17.

Homocystinuria presenting as a calcified right atrial mass

Tahleel Altaf Shera  1 , Naseer Ahmed Choh  1 , Faiz Altaf Shera  1 , Azher Maqbool Khan  1
Affiliations
Case Reports

Homocystinuria presenting as a calcified right atrial mass

Tahleel Altaf Shera et al. Ann Pediatr Cardiol. 2018 May-Aug.

Abstract

Homocystinuria is a genetic inborn error of metabolism due to the deficiency of cystathionine β-synthase resulting in increased serum homocysteine and methionine and decreased cysteine which predisposes affected individuals to arterial and venous thromboembolic phenomena. We present a case of homocystinuria who presented to us as a calcified right atrial mass during the evaluation for lower respiratory tract infection. Our case reveals an unusual mix of findings using imaging with multiple detector computed tomography and radiographs.

Keywords: Calcified cardiac mass; cardiac thrombus; homocystinuria.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Computed tomography showing the calcified right atrial mass with a calcified tail extending into superior vena cava, bronchiectasis seen in the right middle lobe
Figure 2
Figure 2
Computed tomography showing bronchiectasis in both lower lobes, with adjacent consolidation on the left side
Figure 3
Figure 3
Diffuse osteopenia in radiograph of both hands
See this image and copyright information in PMC

References

    1. Watts MA, Innes BJ. Calcified atrial thrombus: Complication of central venous hyperalimentation. Tex Heart Inst J. 1984;1s1:76–9. - PMC - PubMed
    1. Panidis IP, Kotler MN, Mintz GS, Ross J. Clinical and echocardiographic features of right atrial masses. Am Heart J. 1984;107:745–58. - PubMed
    1. Tao TY, Yahyavi-Firouz-Abadi N, Singh GK, Bhalla S. Pediatric cardiac tumors: Clinical and imaging features. Radiographics. 2014;34:1031–46. - PubMed
    1. Peters PJ, Reinhardt S. The echocardiographic evaluation of intracardiac masses: A review. J Am Soc Echocardiogr. 2006;19:230–40. - PubMed
    1. Mudd SH, Skovby F, Levy HL, Pettigrew KD, Wilcken B, Pyeritz RE, et al. The natural history of homocystinuria due to cystathionine beta-synthase deficiency. Am J Hum Genet. 1985;37:1–31. - PMC - PubMed

Publication types