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. 2018 May-Aug;11(2):217-218.
doi: 10.4103/apc.APC_168_17.

Cardiac involvement in hypereosinophilic syndrome

Mohamad Jihad Mansour  1   2 , Malek Rahal  2 , Elie Chammas  1   2 , Omar Hamoui  2 , Wael Aljaroudi  2
Affiliations

Cardiac involvement in hypereosinophilic syndrome

Mohamad Jihad Mansour et al. Ann Pediatr Cardiol. 2018 May-Aug.

Abstract

A 9-year-old boy with hypereosinophilic syndrome (HES) was referred for cardiac magnetic resonance (CMR) imaging following an abnormal echocardiogram that showed a large mass layered on the inferolateral wall of the left ventricle, causing secondary severe mitral regurgitation. Cardiac involvement in HES usually affects the ventricular apex. In our case, CMR confirmed the presence of a large mural thrombus of 0.9 cm × 4.2 cm. This unusual cardiac involvement in HES was diagnosed in its intermediate thrombotic stage. CMR is very sensitive and specific in staging the disease. It explained the etiology of mitral regurgitation and guided therapy, especially when echocardiography was nonconclusive.

Keywords: Cardiac involvement; cardiac magnetic resonance; hypereosinophilic syndrome.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Transthoracic echocardiogram apical four-chamber view showing a large mass (arrows) on the inferolateral wall attached to the mitral valve leaflet
Figure 2
Figure 2
Cardiac magnetic resonance showing large thrombus (arrows) attached to the basal-distal inferolateral wall of the left ventricle and the posterior mitral valve leaflet, causing severe secondary mitral regurgitation (arrowheads)
Figure 3
Figure 3
Cardiac magnetic resonance showing large hypointense mural thrombus (arrows) layered on the ventricular endocardium with the hyperintense signal of the subendocardium consistent with inflammation and/or scar (arrowheads)
See this image and copyright information in PMC

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