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. 2019 May;133(3):775-776.
doi: 10.1007/s00414-018-1878-5. Epub 2018 Jun 20.

Genetic polymorphism of 15 autosomal short tandem repeats in Baloch population of Pakistan

Aleena Ahmad Khan  1 , Rukhsana Perveen  2 , Nadeem Sheikh  2 , Babar Hilal Ahmad Abbasi  3 , Zunaira Batool  2 , Muhammad Shahzad  2 , Sana Kaleem  2
Affiliations

Genetic polymorphism of 15 autosomal short tandem repeats in Baloch population of Pakistan

Aleena Ahmad Khan et al. Int J Legal Med. 2019 May.

Abstract

Allele frequencies and forensic statistical parameters of 15 autosomal short tandem repeats (STRs) were evaluated in 200 genetically unrelated individuals of the Baloch population of Pakistan. Total 155 alleles were observed with allele frequencies ranged from 0.003 to 0.425. Among the 15 STRs, D2S1338 was found to be the most polymorphic and discriminating locus while TPOX was the least polymorphic and discriminating locus. The combined power of discrimination (CPD), combined power of exclusion (CPE), and combined matching probability (CMP) were found to be 0.9999999999999999978, 0.999994252, and 2.14012 × 10-18, respectively. No significant deviation from Hardy-Weinberg Equilibrium (HWE) was observed except for locus D21S11. Additionally, a correlation between previously published data and Baloch population is also presented.

Keywords: Autosomal STRs; Baloch population; Forensic; Genetic polymorphism; Pakistan.

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