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Comment
. 2018 Jun 19;48(6):1065-1067.
doi: 10.1016/j.immuni.2018.05.014.

Mast Cells Reveal Their Past Selves

Anja A Wolf  1 , Helen S Goodridge  2
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Mast Cells Reveal Their Past Selves

Anja A Wolf et al. Immunity. .
Free article

Abstract

Mast cells have been thought to derive from bone marrow hematopoietic stem cells. In this issue of Immunity, Gentek et al. (2018) reveal that mast cells have dual developmental origins in primitive and definitive hematopoiesis and that adult mast cell maintenance is largely bone marrow independent.

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