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Comparative Study
. 2019 Jun;24(6):630-637.
doi: 10.1111/nep.13429. Epub 2019 Apr 24.

Health-related quality of life and health utility of Chinese patients undergoing nocturnal home haemodialysis in comparison with other modes of dialysis

Carlos K H Wong  1 , Julie Y Chen  1   2 , Samuel K S Fung  3 , Wai Kei Lo  4 , Sing Leung Lui  4 , Tak Mao Chan  5 , Yuk Lun Cheng  6 , Irene Kong  3 , Eric Y F Wan  1 , Cindy L K Lam  1
Affiliations
Comparative Study

Health-related quality of life and health utility of Chinese patients undergoing nocturnal home haemodialysis in comparison with other modes of dialysis

Carlos K H Wong et al. Nephrology (Carlton). 2019 Jun.

Abstract

Background: To compare the health-related quality of life (HRQOL) and health utility of Chinese patients with end-stage renal disease (ESRD) undergoing nocturnal home haemodialysis (Home HD) against those patients undergoing other modes of dialysis.

Methods: Chinese ESRD patients undergoing Home HD were recruited in renal specialist outpatient clinics at three public hospitals in Hong Kong. SF-12 Health Survey (SF-12) was used to measure HRQOL and generate the SF-6D heath utility score. Mean scores of SF-12 domains, physical and mental component summary and SF-6D health utility of 41 patients undergoing Home HD were compared with available scores of patients receiving other forms of dialysis, namely, peritoneal dialysis (PD) (n = 103), hospital in-centre HD (n = 135) or community in-centre HD (n = 118). Adjusted linear regression models were used to examine the impact of mode of dialysis on the HRQOL and health utility scores, accounting for the sociodemographic and clinical characteristics.

Results: ESRD patients undergoing PD and community in-centre HD had better health utility, physical and mental component summary scores than the hospital in-centre HD. Adjusted analysis showed that hospital in-centre HD reported worse physical component summary and health utility scores when compared with PD and community in-centre HD.

Conclusion: HRQOL and health utility scores of patients undergoing Home HD were similar to those undergoing PD and community in-centre HD. Better physical aspects of HRQOL and health utility was observed in PD and community-based HD than hospital in-centre HD, providing evidence for the increase in capacity of non-hospital-based HD, which provided flexibility as well as patient centredness and empowerment in Hong Kong.

Keywords: dialysis; end-stage renal disease; nocturnal home haemodialysis; patient-reported outcome; quality of life.

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