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. 2018 May;8(4):457-460.
doi: 10.21037/qims.2018.05.05.

Huge and recurrent undifferentiated carcinoma with osteoclast-like giant cells of the pancreas

Lan Zhang  1 , Jeong Min Lee  2 , Jeong Hee Yoon  2 , Ijin Joo  2 , Hyo Jin Kang  2 , Joon Koo Han  2 , Sun Kyung Jeon  2
Affiliations

Huge and recurrent undifferentiated carcinoma with osteoclast-like giant cells of the pancreas

Lan Zhang et al. Quant Imaging Med Surg. 2018 May.
No abstract available

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Huge undifferentiated carcinoma with osteoclast-like giant cells prior to operation. (A) CT plain scan shows a huge, well-defined, cystic and solid mass in the left upper quadrant of the abdomen; (B) contrast-enhanced CT demonstrates multiple cystic vesicles with septations with inhomogeneous enhancement of the solid portion within the tumor; (C) T2-weighted imaging (T2WI) shows a large mass with miscellaneous high signal intensity; (D) T1-weighted imaging (T2WI) shows patchy high signal within the low signal intensity tumor; (E) diffusion-weighted imaging (DWI) shows a mass with slightly high signal intensity; (F,G) contrast-enhanced MRI demonstrates that the septations and capsule of the tumor enhanced markedly; (H) 18F-FDG PET-CT shows the high uptake within the tumor.
Figure 2
Figure 2
Gross findings show a 12 cm × 9 cm × 9 cm mass in the pancreatic tail along with cysts filled with hemorrhage and necrosis on the cut surface (A), pathologic examination reveals that the tumor is composed of pleomorphic mononuclear cells and osteoclast-like giant cells (hematoxylin and eosin staining, magnification ×20) (B).
Figure 3
Figure 3
Recurrent undifferentiated carcinoma with osteoclast-like giant cells. (A) CT plain scan depicts a huge, multifocal, recurrent intraperitoneal mass in the left abdomen; (B) contrast-enhanced CT shows a large cystic and solid mass with inhomogeneous enhancement.
See this image and copyright information in PMC

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References

    1. Bosman FT, Carneiro F, Hruban RH, Theise ND. WHO Classification of Tumors of the Digestive System. 4th edition. Lyon: International Agency for Research on Cancer (IARC), 2010:281-95.
    1. Maksymov V, Khalifa MA, Bussey A, Carter B, Hogan M. Undifferentiated (anaplastic) carcinoma of the pancreas with osteoclast-like giant cells showing various degree of pancreas duct involvement. A case report and literature review. JOP 2011;12:170-6. - PubMed
    1. Gao HQ, Yang YM, Zhuang Y, Liu P. Locally advanced undifferentiated carcinoma with osteoclast-like giant cells of the pancreas. World J Gastroenterol 2015;21:694-8. 10.3748/wjg.v21.i2.694 - DOI - PMC - PubMed
    1. Verbeke CS, Menon KV. Osteoclast-like giant cell tumour of the pancreas: an undifferentiated carcinoma of duct epithelial origin. Pancreatology 2006;6:254; author reply 254. 10.1159/000091963 - DOI - PubMed
    1. Njoumi N, Elalami FH, Attolou G, Saoud O, Elabsi M, Echarrab M, Elouannani M, Errougani A, Amraoui M, Chkoff MR. Undifferentiated pancreatic carcinoma with osteoclast-like giant cells: a case report. J Gastrointest Cancer 2014;45 Suppl 1:96-8. 10.1007/s12029-013-9572-9 - DOI - PMC - PubMed

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