Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 May-Aug;11(2):144-149.
doi: 10.4103/ojo.OJO_143_2017.

Influence of total intraocular lens diameter on efficacy and safety for in the bag cataract surgery

Efstathios Vounotrypidis  1 , Carlo Lackerbauer  1 , Daniel Kook  1 , Martin Dirisamer  1 , Siegfried Priglinger  1 , Wolfgang J Mayer  1
Affiliations

Influence of total intraocular lens diameter on efficacy and safety for in the bag cataract surgery

Efstathios Vounotrypidis et al. Oman J Ophthalmol. 2018 May-Aug.

Abstract

Context: Intraocular lenses with variable total diameter are supposed to fit better in the capsular bag and lead to fewer complications.

Aims: This study aims to investigate the efficacy and the safety of an intraocular lens model with variable total diameter.

Settings and design: Prospective randomized intraindividual study.

Subjects and methods: Thirty-two eyes of sixteen patients with bilateral age-related cataract received standard cataract surgery with implantation of an intraocular lens with a standard diameter in one eye (Quatrix®, Group A) and with a variable total diameter in the fellow eye (Quatrix Evolutive®, Group B). Primary study endpoints included evaluation of refraction stability and posterior capsule opacification (PCO) over a follow-up period of 6 months.

Statistical analysis used: SPSS (Version 19.0) was used for statistical analysis.

Results: Uncorrected and corrected distant visual acuity after 6 months were 0.24 and 0.1 LogMAR in Group A and 0.23 and 0.09 LogMAR in Group B, respectively. The objective and manifest spherical equivalent (OSE, MSE) 6 months postoperatively were + 0.65 D and + 0.62 D in Group A compared to + 0.33 D and + 0.33 D in Group B respectively (P = 0.665 for OSE, P = 0.208 for MSE). PCO-index increased statistically significant in both groups (P = 0.004 in Group A, P = 0.046 in Group B), but the difference of PCO-index between both groups was not statistically significant (P = 0.569).

Conclusions: An intraocular lens with a variable total diameter shows good visual outcomes and safety performance as well as same outcomes concerning postoperative refractive stability and development of PCO compared to an intraocular lens with standard total diameter.

Keywords: Biometry; intraocular lens; intraocular lense diameter; posterior capsule opacification; refraction stability.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Development of the mean uncorrected and corrected distance visual acuity over the follow up period with regard to the intraocular lens-model
Figure 2
Figure 2
Distribution of the spherical equivalent of the manifest and objective refraction (D) at the last follow up examination (6 months) according to the intraocular lens-model
Figure 3
Figure 3
Distribution of the final anterior chamber depth (mm) after 6 months with regard to its preoperative value according to the intraocular lens-model. The outlier in this figure corresponds to the one patient that developed a prolonged inflammatoric reaction after surgery
Figure 4
Figure 4
Distribution of the final anterior chamber depth (mm) regarding the preoperative axial length (mm) according to the intraocular lens-model. The intraocular lens with the variable diameter demonstrates a lower deviation of postoperative anterior chamber depth in eyes with higher ametropia. The outlier corresponds to the patient that developed a prolonged inflammatoric reaction after surgery
Figure 5
Figure 5
Development of the posterior capsule opacification-index according to intraocular lens-model
See this image and copyright information in PMC

References

    1. Apple DJ, Escobar-Gomez M, Zaugg B, Kleinmann G, Borkenstein AF. Modern cataract surgery: Unfinished business and unanswered questions. Surv Ophthalmol. 2011;56:S3–53. - PubMed
    1. Vass C, Menapace R, Schmetterer K, Findl O, Rainer G, Steineck I, et al. Prediction of pseudophakic capsular bag diameter based on biometric variables. J Cataract Refract Surg. 1999;25:1376–81. - PubMed
    1. Assia EI, Apple DJ. Side-view analysis of the lens. I. The crystalline lens and the evacuated bag. Arch Ophthalmol. 1992;110:89–93. - PubMed
    1. Galand A, Bonhomme L, Collée M. Direct measurement of the capsular bag. J Am Intraocul Implant Soc. 1984;10:475–6. - PubMed
    1. Ram J, Apple DJ, Peng Q, Visessook N, Auffarth GU, Schoderbek RJ, Jr, et al. Update on fixation of rigid and foldable posterior chamber intraocular lenses. Part II: Choosing the correct haptic fixation and intraocular lens design to help eradicate posterior capsule opacification. Ophthalmology. 1999;106:891–900. - PubMed