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. 2013 Oct 18;1(1):17-22.
doi: 10.1002/ams2.1. eCollection 2014 Jan.

Prevalence of metabolic syndrome in stroke patients: a prospective multicenter study in Japan

Takeshi Takahashi  1 , Masahiro Harada  1 , Takaaki Kikuno  2 , Makoto Ujihara  3 , Daikai Sadamitsu  4 , Yasuhiro Manabe  5 , Masahiro Yasaka  6 , Hayato Takayama  7 , Shozo Kobori  8 , Eiichi Araki  9
Affiliations

Prevalence of metabolic syndrome in stroke patients: a prospective multicenter study in Japan

Takeshi Takahashi et al. Acute Med Surg. .

Abstract

Aims: The fact that Metabolic Syndrome (MetS) increases the risk of atherosclerosis has been epidemiologically studied and proven; however, a prospective study on the prevalence of MetS in stroke patients has never been conducted because of the difficulty in diagnosis under critical illness in the acute phase. Therefore, we conducted a prospective multicenter study to investigate the prevalence of MetS in stroke patients with modified diagnostic criteria for MetS.

Methods: Stroke patients admitted in the seven participating Emergency and Critical Care Centers within the two years from April 2007 were registered in this study as a prospective multicenter study. Inclusion criteria were 50 to 89 year-old stroke patients who presented within three days from the onset of symptoms. A total of 992 subjects were classified according to the stroke type and the prevalence of MetS and the associated risk factors were investigated. The participants in a medical checkup without any history of a stroke were enrolled as the control group, and compared between the two groups.

Results: The prevalence of MetS as well as hyperglycemia and dyslipidemia in the infarction group was significantly higher than that in the non-stroke group. While the hemorrhage group showed no significant difference in the prevalence of MetS, only hypertension was significantly high. According to a subtype analysis, there is a significant correlation between waist circumference increment of the stroke patients and the prevalence of the risk factors of hypertension, hyperglycemia and dyslipidemia.

Conclusions: Different risk factors are significantly related to the type of stroke.

Keywords: Diabetes; dyslipidemia; hypertension; metabolic syndrome; obesity.

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