Hepatocellular carcinoma in young, mentally retarded HBsAg carriers without cirrhosis
- PMID: 2993146
- DOI: 10.1002/hep.1840050519
Hepatocellular carcinoma in young, mentally retarded HBsAg carriers without cirrhosis
Abstract
In a Californian institution for the mentally retarded, surveillance by autopsy of all deaths (n = 138) identified three cases of hepatocellular carcinoma. Hepatocellular carcinoma cases occurred in young (mean age = 26 years) male carriers of HBsAg and were not associated with cirrhosis. They were of the nonfibrolamellar oncocytic type and were rapidly fatal. Hepatocellular carcinoma incidence in HBsAg carriers was estimated to be 246 times greater than United States males.
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