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. 2018 Jun 22;8(6):e020954.
doi: 10.1136/bmjopen-2017-020954.

Effect of Baduanjin exercise on cognitive function in patients with post-stroke cognitive impairment: study protocol for a randomised controlled trial

Guohua Zheng #  1 , Yuhui Zheng #  2 , Zhenyu Xiong  2 , Bingzhao Ye  2 , Jing Tao  2 , Lidian Chen  3
Affiliations

Effect of Baduanjin exercise on cognitive function in patients with post-stroke cognitive impairment: study protocol for a randomised controlled trial

Guohua Zheng et al. BMJ Open. .

Abstract

Introduction: Poststroke cognitive impairment is one of the most common complications in stroke survivors, and >65% of these patients suffer from cognitive impairment at 12 months following onset, which strongly affects the rehabilitation of their motor function and quality of life. Therefore, it is important to improve the cognitive ability of stroke survivors. As an important component of traditional Chinese Qigong exercises, characterised by the coordination of mind and body with a low exercise intensity, Baduanjin has the potential benefit of improving cognitive ability for patients who had a stroke with cognitive impairment. The primary purpose of this study is to investigate the effectiveness and safety of Baduanjin training on the cognitive function of stroke survivors.

Method and analysis: This study is designed as a randomised, two-arm parallel controlled trial with allocation concealment and assessors blinding. A total of 48 participants will be recruited and randomly allocated into the Baduanjin exercise intervention or control group. Baduanjin intervention will last 24 weeks with a frequency of 3 days a week and 40 min a day. Global cognitive function and the specific domains of cognition (ie, memory, processing speed, execution, attention and visuospatial ability) will be measured at baseline, 8, 16 and, 24 weeks after intervention and after an additional 4-week follow-up period, while the motor function and quality of life will be measured at baseline, 24 weeks after intervention and after an additional 4-week follow-up period.

Ethics and dissemination: Ethics approval was obtained from the Ethics Committee of Fujian University of Traditional Chinese Medicine Subsidiary Rehabilitation Hospital (approval number: 2016KY-022-01). The findings will be disseminated through peer-reviewed publications and at scientific conferences.

Trial registration number: ChiCTR-INR-16009364; Pre-results.

Keywords: baduanjin exercise; cognitive impairment after stroke; randomized controlled trial.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Study design.
Figure 2
Figure 2
Schedule of enrolment, interventions and assessments. t1=−2(−1) weeks, 0=baseline, t1=week B, t2=week 16, t3=end of treatment week 24, t4=follow-up week 28.
Figure 3
Figure 3
Ten postures of Baduanjin.
See this image and copyright information in PMC

References

    1. Feigin VL, Forouzanfar MH, Krishnamurthi R, et al. Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet 2014;383:245–55. 10.1016/S0140-6736(13)61953-4 - DOI - PMC - PubMed
    1. Jin YP, Di Legge S, Ostbye T, et al. The reciprocal risks of stroke and cognitive impairment in an elderly population. Alzheimers Dement 2006;2:171–8. 10.1016/j.jalz.2006.03.006 - DOI - PubMed
    1. Geusgens CA, van Heugten CM, Cooijmans JP, et al. Transfer effects of a cognitive strategy training for stroke patients with apraxia. J Clin Exp Neuropsychol 2007;29:831–41. 10.1080/13803390601125971 - DOI - PubMed
    1. Cumming TB, Brodtmann A, Darby D, et al. The importance of cognition to quality of life after stroke. J Psychosom Res 2014;77:374–9. 10.1016/j.jpsychores.2014.08.009 - DOI - PubMed
    1. Kavirajan H, Schneider LS. Efficacy and adverse effects of cholinesterase inhibitors and memantine in vascular dementia: a meta-analysis of randomised controlled trials. Lancet Neurol 2007;6:782–92. 10.1016/S1474-4422(07)70195-3 - DOI - PubMed

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