Code Under Construction: Neural Coding Over Development

Abstract

Developing animals must begin to interact with the world before their neural development is complete. This means they must build neural codes appropriate for turning sensory inputs into motor outputs adaptively as their neural hardware matures. We review some recent progress in the understanding of the relationship between neural coding and neural circuit development. We focus particularly on neural coding in the context of topographic maps and spontaneous activity, as well as receptive field and circuit development, drawing on examples from both mammalian visual cortex and fish optic tectum. Overall we suggest that neural coding strategies during development may be highly dynamic.

Keywords: Bayesian inference; circuit development; neural coding; receptive field; spontaneous activity; topographic map.