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. 2018 Oct;45(11):2009-2024.
doi: 10.1007/s00259-018-4070-8.

Guidelines on nuclear medicine imaging in neuroblastoma

Zvi Bar-Sever  1 , Lorenzo Biassoni  2 , Barry Shulkin  3 , Grace Kong  4 , Michael S Hofman  4 , Egesta Lopci  5 , Irina Manea  6 , Jacek Koziorowski  6 , Rita Castellani  7 , Ariane Boubaker  8 , Bieke Lambert  9 , Thomas Pfluger  10 , Helen Nadel  11 , Susan Sharp  12 , Francesco Giammarile  13
Affiliations

Guidelines on nuclear medicine imaging in neuroblastoma

Zvi Bar-Sever et al. Eur J Nucl Med Mol Imaging. 2018 Oct.

Abstract

Nuclear medicine has a central role in the diagnosis, staging, response assessment and long-term follow-up of neuroblastoma, the most common solid extracranial tumour in children. These EANM guidelines include updated information on 123I-mIBG, the most common study in nuclear medicine for the evaluation of neuroblastoma, and on PET/CT imaging with 18F-FDG, 18F-DOPA and 68Ga-DOTA peptides. These PET/CT studies are increasingly employed in clinical practice. Indications, advantages and limitations are presented along with recommendations on study protocols, interpretation of findings and reporting results.

Keywords: 123I-MIBG; 18F-DOPA PET/CT; 18F-FDG PET/CT; 68Ga-DOTA TATE PET/CT; Children; Guidelines; Neuroblastoma.

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