Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985;13(1-2):23-5.
doi: 10.1159/000118157.

Brain noradrenergic activity in wakefulness and paradoxical sleep: the effect of clonidine

J M Gaillard

Brain noradrenergic activity in wakefulness and paradoxical sleep: the effect of clonidine

J M Gaillard. Neuropsychobiology. 1985.

Abstract

Several experiments in which the effects of clonidine (CLN) have been studied in the rat and in man are summarized. CLN inhibits paradoxical sleep (PS) both in the rat and in man. This inhibition is followed by a rebound, but with a different time course in the two species. Wakefulness (W) is enhanced after some critical doses of CLN, and decreased after higher doses. These effects of CLN suggest that alpha 2-adrenoceptors are involved in the regulation of W and PS.

PubMed Disclaimer

LinkOut - more resources