Deep Venous Thrombosis
- PMID: 29939530
- Bookshelf ID: NBK507708
Deep Venous Thrombosis
Excerpt
Deep vein thrombosis (DVT) is an obstructive disease with a hindering venous reflux mechanism. DVT usually involves the lower limb venous system, with clot formation originating in a deep calf vein and propagating proximally. See Image. Deep Vein Thrombosis. It is a common venous thromboembolic (VTE) disorder with an incidence of 1.6 per 1000 annually. The rate of particular site involvement depends on the anatomical location as follows, distal veins 40%, popliteal 16%, femoral 20%, common femoral 20%, and iliac veins 4%.
A deep-vein thrombosis (DVT) is a blood clot that forms within the deep veins, usually of the leg, but can occur in the arms and the mesenteric and cerebral veins. Deep-vein thrombosis is a common and important disease. It is part of the venous thromboembolism disorders, representing the third most common cause of death from cardiovascular disease after heart attacks and stroke. Even in patients who do not get pulmonary emboli, recurrent thrombosis and "post-thrombotic syndrome" are major causes of morbidity. Deep-vein thrombosis is a major medical problem accounting for most cases of pulmonary embolism. Only through early diagnosis and treatment can the morbidity be reduced.
Copyright © 2025, StatPearls Publishing LLC.
Conflict of interest statement
Sections
- Continuing Education Activity
- Introduction
- Etiology
- Epidemiology
- Pathophysiology
- Histopathology
- History and Physical
- Evaluation
- Treatment / Management
- Differential Diagnosis
- Surgical Oncology
- Staging
- Prognosis
- Complications
- Postoperative and Rehabilitation Care
- Deterrence and Patient Education
- Enhancing Healthcare Team Outcomes
- Review Questions
- References
References
-
- Albricker ACL, Freire CMV, Santos SND, Alcantara ML, Saleh MH, Cantisano AL, Teodoro JAR, Porto CLL, Amaral SID, Veloso OCG, Petisco ACGP, Barros FS, Barros MVL, Souza AJ, Sobreira ML, Miranda RB, Moraes D, Verrastro CGY, Mançano AD, Lima RSL, Muglia VF, Matushita CS, Lopes RW, Coutinho AMN, Pianta DB, Santos AASMDD, Naves BL, Vieira MLC, Rochitte CE. Joint Guideline on Venous Thromboembolism - 2022. Arq Bras Cardiol. 2022 Apr;118(4):797-857. - PMC - PubMed
-
- Stubbs MJ, Mouyis M, Thomas M. Deep vein thrombosis. BMJ. 2018 Feb 22;360:k351. - PubMed
-
- Parker K, Thachil J. The use of direct oral anticoagulants in chronic kidney disease. Br J Haematol. 2018 Oct;183(2):170-184. - PubMed
Publication types
LinkOut - more resources
Full Text Sources