Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Biochemistry, Collagen Synthesis

Marlyn Wu  1 , Kelly Cronin  2 , Jonathan S. Crane  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Biochemistry, Collagen Synthesis

Marlyn Wu et al.
Free Books & Documents

Excerpt

Collagen is protein molecules made up of amino acids. It provides structural support to the extracellular space of connective tissues. Due to its rigidity and resistance to stretching, it is the perfect matrix for skin, tendons, bones, and ligaments.

Collagen can be further divided into several groups depending on the type of structures they form. There are 28 various types of collagen that have been discovered, but by far, the most common are types I through IV, with type I comprising over 90% of the collagen in the human body.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Marlyn Wu declares no relevant financial relationships with ineligible companies.

Disclosure: Kelly Cronin declares no relevant financial relationships with ineligible companies.

Disclosure: Jonathan Crane declares no relevant financial relationships with ineligible companies.

References

    1. Nagaoka I, Tsuruta A, Yoshimura M. Chondroprotective action of glucosamine, a chitosan monomer, on the joint health of athletes. Int J Biol Macromol. 2019 Jul 01;132:795-800. - PubMed
    1. Mäkitie RE, Costantini A, Kämpe A, Alm JJ, Mäkitie O. New Insights Into Monogenic Causes of Osteoporosis. Front Endocrinol (Lausanne) 2019;10:70. - PMC - PubMed
    1. Subramanian S, Anastasopoulou C, Viswanathan VK. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. Feb 6, Osteogenesis Imperfecta. - PubMed
    1. Saghaleini SH, Dehghan K, Shadvar K, Sanaie S, Mahmoodpoor A, Ostadi Z. Pressure Ulcer and Nutrition. Indian J Crit Care Med. 2018 Apr;22(4):283-289. - PMC - PubMed
    1. Szulc P. Bone turnover: Biology and assessment tools. Best Pract Res Clin Endocrinol Metab. 2018 Oct;32(5):725-738. - PubMed

Publication types

LinkOut - more resources