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Book

Syndrome of Inappropriate Antidiuretic Hormone Secretion

Muhammad Yasir  1 , Oren J. Mechanic  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Syndrome of Inappropriate Antidiuretic Hormone Secretion

Muhammad Yasir et al.
Free Books & Documents

Excerpt

Syndrome of inappropriate antidiuretic hormone ADH release (SIADH) is a condition defined by the unsuppressed release of antidiuretic hormone (ADH) from the pituitary gland or nonpituitary sources or its continued action on vasopressin receptors. The condition was first detected in two patients with lung cancer by William Schwartz and Frederic Bartter in 1967. They developed the classic Schwartz and Bartter criteria for the diagnosis of SIADH, which has not changed. SIADH is characterized by impaired water excretion leading to hyponatremia with hypervolemia or euvolemia.

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Conflict of interest statement

Disclosure: Muhammad Yasir declares no relevant financial relationships with ineligible companies.

Disclosure: Oren Mechanic declares no relevant financial relationships with ineligible companies.

References

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