Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Hepatic Chemoembolization

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Hepatic Chemoembolization

Michael Young et al.
Free Books & Documents

Excerpt

Chemoembolization is a technique that involves injecting medication into the feeding arteries of a tumor or the injection of particles designed to slow or stop the arterial supply of oxygen and nutrients to that tumor. Hepatic chemoembolization, a procedure that has been performed since the late 1970s, is one of several techniques used to treat either primary liver cancer or cancer metastatic to the liver. The most common primary liver cancer is hepatocellular carcinoma. Common types of liver metastases include those from the colon, breast, carcinoid, muscle sarcomas, and melanoma.

Arterial chemoembolization can also be termed transarterial chemoembolization, a method of arterial-directed therapy (ADT). Other ADT methods include:

  1. Injection of particles alone without chemotherapy, called transarterial embolization or bland embolization

  2. Injection of radioactive particles without chemotherapy, called transarterial radioembolization, or occasionally referred to as the radioactive particle used, eg, Yttrium-90 (Y-90)

PubMed Disclaimer

Conflict of interest statement

Disclosure: Michael Young declares no relevant financial relationships with ineligible companies.

Disclosure: Savio John declares no relevant financial relationships with ineligible companies.

References

    1. Reuter SR. The current status of angiography in the evaluation of cancer patients. Cancer. 1976 Jan;37(1 suppl):532-41. - PubMed
    1. Friedman MA, Volberding PA, Cassidy MJ, Resser KJ, Wasserman TH, Phillips TL. Therapy for hepatocellular cancer with intrahepatic arterial adriamycin and 5-fluorouracil combined with whole-liver irradiation: a Northern California Oncology Group Study. Cancer Treat Rep. 1979 Nov-Dec;63(11-12):1885-8. - PubMed
    1. Wang S, He X, Li Z, Peng Z, Tam NL, Sun C, Hu A, Huang J. Characterization of the middle hepatic artery and its relevance to living donor liver transplantation. Liver Transpl. 2010 Jun;16(6):736-41. - PubMed
    1. Mazzaferro V, Regalia E, Doci R, Andreola S, Pulvirenti A, Bozzetti F, Montalto F, Ammatuna M, Morabito A, Gennari L. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med. 1996 Mar 14;334(11):693-9. - PubMed
    1. Okuda K, Ohtsuki T, Obata H, Tomimatsu M, Okazaki N, Hasegawa H, Nakajima Y, Ohnishi K. Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients. Cancer. 1985 Aug 15;56(4):918-28. - PubMed

Publication types

LinkOut - more resources