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Book

Aliskiren (Archived)

Tibb F. Jacobs  1 , Blake H. Salisbury  2 , Jamie M. Terrell  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Affiliations
Book

Aliskiren (Archived)

Tibb F. Jacobs et al.

Excerpt

FDA-Approved Indications

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Conflict of interest statement

Disclosure: Tibb Jacobs declares no relevant financial relationships with ineligible companies.

Disclosure: Blake Salisbury declares no relevant financial relationships with ineligible companies.

Disclosure: Jamie Terrell declares no relevant financial relationships with ineligible companies.

References

    1. Zhao Q, Shen J, Lu J, Jiang Q, Wang Y. Clinical efficacy, safety and tolerability of Aliskiren Monotherapy (AM): an umbrella review of systematic reviews. BMC Cardiovasc Disord. 2020 Apr 17;20(1):179. - PMC - PubMed
    1. Łukawski K, Raszewski G, Czuczwar SJ. Effect of aliskiren, a direct renin inhibitor, on the protective action of antiepileptic drugs against pentylenetetrazole-induced clonic seizures in mice. Fundam Clin Pharmacol. 2019 Apr;33(2):191-198. - PubMed
    1. Yamashita S, Biswas KB, Nabi AHMN, Nakagawa T, Suzuki F, Ebihara A. Aliskiren reduces the release of soluble (pro)renin receptor from human umbilical vein endothelial cells. Biomed Rep. 2018 Sep;9(3):247-252. - PMC - PubMed
    1. Nakano D, Nishiyama A. A novel role of renin inhibitor in the complement cascade. Kidney Int. 2018 Oct;94(4):650-652. - PubMed
    1. Bjerre HL, Christensen JB, Buus NH, Simonsen U, Su J. The role of aliskiren in the management of hypertension and major cardiovascular outcomes: a systematic review and meta-analysis. J Hum Hypertens. 2019 Nov;33(11):795-806. - PubMed

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