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Book

Dakin Solution

Michael Keyes  1 , Zohaib Jamal  2 , Rachel Thibodeau
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Dakin Solution

Michael Keyes et al.
Free Books & Documents

Excerpt

Dakin solution, also called Dakin fluid or Carrel-Dakin fluid, is a dilute sodium hypochlorite (NaClO) solution commonly known as bleach. The sodium peroxide (NaO) and hydrochloric acid (HCl) mixture produces sodium hypochlorite. The main active agent in Dakin solution is created when the chlorine reacts with water in the environment to form hypochlorous acid (HClO). This hypochlorous acid produces a potent antibacterial effect in tissues. This activity reviews the mechanism of action, adverse event profile, toxicity, and administration of Dakin solution as it applies to the clinical setting.

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Conflict of interest statement

Disclosure: Michael Keyes declares no relevant financial relationships with ineligible companies.

Disclosure: Zohaib Jamal declares no relevant financial relationships with ineligible companies.

Disclosure: Rachel Thibodeau declares no relevant financial relationships with ineligible companies.

References

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    1. Sabbatani S, Fiorino S. The treatment of wounds during World War I. Infez Med. 2017 Jun 01;25(2):184-192. - PubMed
    1. Duarte B, Formiga A, Neves J. Dakin's solution in the treatment of severe diabetic foot infections. Int Wound J. 2020 Apr;17(2):277-284. - PMC - PubMed
    1. McCullough M, Carlson GW. Dakin's solution: historical perspective and current practice. Ann Plast Surg. 2014 Sep;73(3):254-6. - PubMed

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