Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2018 Jul;138(7):1470-1472.
doi: 10.1016/j.jid.2018.03.003.

Next Time, Save Mushrooms for the Pizza!

Thomas J Hornyak  1
Affiliations
Free article
Comment

Next Time, Save Mushrooms for the Pizza!

Thomas J Hornyak. J Invest Dermatol. 2018 Jul.
Free article

Abstract

Mann et al. (2018) use recombinant human tyrosinase to screen for novel inhibitors of pigmentation. They develop thiamidol, a new thiazolyl-resorcinol derivative, that is a submicromolar tyrosinase inhibitor and effective for treating solar lentigines. Thiamidol and established inhibitors of pigmentation exhibit substantially different activities on human and mushroom tyrosinase, supporting use of the human enzyme in high-throughput screens.

PubMed Disclaimer

Comment on

Publication types

Substances

LinkOut - more resources