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Comment
. 2018 Aug;28(8):589-591.
doi: 10.1016/j.tcb.2018.06.004. Epub 2018 Jun 22.

Yeast and Human Nuclear Pore Complexes: Not So Similar After All

Yaron Shav-Tal  1 , Timir Tripathi  2
Affiliations
Comment

Yeast and Human Nuclear Pore Complexes: Not So Similar After All

Yaron Shav-Tal et al. Trends Cell Biol. 2018 Aug.

Abstract

Nucleoporin subunits that generate the nuclear pore complex (NPC) are highly conserved in evolution. High-resolution structures of the NPC are available, but the actual NPC composition in yeast has only been quantified recently. Two studies reveal major differences between species, suggesting high flexibility in NPC structures during evolution.

Keywords: NPC structure; evolution; nuclear pore complex; nucleoporins.

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