doi: 10.1007/BF01534845.
Transformation associated p53 protein is encoded by a gene on human chromosome 17
- PMID: 2994241
- DOI: 10.1007/BF01534845
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Transformation associated p53 protein is encoded by a gene on human chromosome 17
Somat Cell Mol Genet.
1985 Sep.
Abstract
The human gene for the transformation-associated p53 phosphoprotein (P53) was assigned to the short arm of chromosome 17 using human-rodent somatic cell hybrids and Southern filter hybridization of cell hybrid DNA. The filters were hybridized to radiolabeled DNA from a genomic clone which contained P53 nucleotide sequences. Hybridization of the probe to a 2.5-kb human DNA fragment in HindIII-digested DNA was used to identify the human P53 gene.
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