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. 1985 Sep;11(5):505-10.
doi: 10.1007/BF01534845.

Transformation associated p53 protein is encoded by a gene on human chromosome 17

S Benchimol, P Lamb, L V Crawford, D Sheer, T B Shows, G A Bruns, J Peacock

Transformation associated p53 protein is encoded by a gene on human chromosome 17

S Benchimol et al. Somat Cell Mol Genet. 1985 Sep.

Abstract

The human gene for the transformation-associated p53 phosphoprotein (P53) was assigned to the short arm of chromosome 17 using human-rodent somatic cell hybrids and Southern filter hybridization of cell hybrid DNA. The filters were hybridized to radiolabeled DNA from a genomic clone which contained P53 nucleotide sequences. Hybridization of the probe to a 2.5-kb human DNA fragment in HindIII-digested DNA was used to identify the human P53 gene.

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